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Marschall Runge, MD, PhD is a cardiologist, molecular biologist, and former CEO of Michigan Medicine. He is the author of The Great Healthcare Disruption (2025), a USA TODAY Best-Seller, and the techno-medical thriller Coded to Kill (Post Hill Press, 2023).

Marschall Runge, MD, PhD is a cardiologist and molecular biologist with four decades of experience in academic medicine. As executive vice president for medical affairs at the University of Michigan, dean of the medical school, and CEO of Michigan Medicine, he led the system through a decade of expansion in digital health, precision medicine, and aging research. His PubMed record runs to nearly 200 peer-reviewed papers and five patents on cardiovascular disease and longevity. He is the author of The Great Healthcare Disruption (2025), a USA TODAY best-seller and Global Book Awards Gold Medal winner, and the techno-medical thriller Coded to Kill (Post Hill Press, 2023). A third nonfiction book on epigenetic clocks is in development.

Marschall Runge, MD, PhD is a cardiologist, molecular biologist, and former CEO of Michigan Medicine, with four decades of experience in American medicine. He earned his PhD in cardiovascular molecular biology at Vanderbilt University and his MD at Johns Hopkins School of Medicine, where he also completed his residency. He was a cardiology fellow at Massachusetts General Hospital.

Dr. Runge served as executive vice president for medical affairs at the University of Michigan, dean of the medical school, and CEO of Michigan Medicine. Under his leadership the health system expanded in digital health, precision medicine, and aging research. His PubMed record runs to nearly 200 peer-reviewed papers and five patents. The early laboratory work identified NADPH oxidase (NOX4)-derived superoxide and mitochondrial DNA damage as upstream drivers of atherosclerosis and vascular aging; later work on Plasminogen Activator Inhibitor-1 (PAI-1) connected those mechanisms to fibrosis and hypertension.

He now leads a multi-omic longevity initiative at Michigan that links cardiorespiratory fitness, methylation arrays, and maternal mtDNA inheritance. His non-fiction book The Great Healthcare Disruption (2025) is a USA TODAY Best-Seller and Global Book Awards Gold Medal winner. His thriller Coded to Kill (Post Hill Press, 2023) is built around the same medical infrastructure he writes about in the nonfiction. A third nonfiction book on epigenetic clocks and biological aging is in development with agent Thomas LeBien.