Cover of The Great Healthcare Disruption by Dr. Marschall Runge
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Topic

The Future of American Healthcare.

Big Tech in care delivery, retail medicine, the restructuring of payers, and the policy choices that will decide who benefits. This is the argument of The Great Healthcare Disruption, drawn from four decades as a clinician, researcher, and CEO of Michigan Medicine. Not a polemic and not a prediction: a working physician's view of what is already happening.

What is actually changing

Healthcare change is not coming; it is here. These are the forces The Great Healthcare Disruption examines: some of them genuine breakthroughs, some hype, some both.

  • AI-driven diagnostics and decision support: what the evidence shows, and where the hype runs ahead
  • Retail and direct-to-consumer medicine: primary care delivered at Walmart, CVS, and Amazon, and what it means for traditional clinics
  • GLP-1 receptor agonists: semaglutide, tirzepatide, and the cardiometabolic shift they are driving
  • Gene therapy and personalized medicine: sickle cell, hemophilia, and the next decade of one-time cures
  • Electronic health records: why they are frustrating, who they serve, and what would make them better
  • Policy frameworks: the federal and state decisions that will determine who benefits
  • The future of academic medicine: teaching hospitals as anchor institutions in an era of consolidation

Questions the book leaves you with

Eight discussion questions close the book, drawn from its "The Takeaway" sections and used in lifelong-learning institutes, healthcare leadership cohorts, and classroom settings. Four of them:

  1. The book argues that "medicine is not just a science and an art; it is also a business." Where does that framing change how you think about the doctor's office, hospital, or insurance company you interact with?
  2. Retail medicine (CVS, Walmart, Amazon) promises convenience. What is the trade-off when your primary-care visit happens at a pharmacy counter versus a continuity-of-care clinic?
  3. Electronic health records frustrate everyone. Whose interests are they actually built to serve?
  4. If you could change one policy lever in American healthcare based on the book's analysis, what would it be?

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