Marschall Runge
Cardiologist, molecular biologist, and former CEO of Michigan Medicine. Forty years of cardiovascular and longevity research, written and spoken for readers outside the lab.
Onstage and on air
Recent talks and broadcasts on the future of American medicine.
C-SPAN Book TV
0:43 in
UCLA · Torrens Forum
10:00 in
Recent coverage
A current sampling. The full press archive has 90+ items across television, radio, podcasts, and print.
Books by Dr. Runge
The Great Healthcare Disruption
Published: Forbes Books, 2025
Healthcare change isn't coming. It's here. Drawing on four decades as a clinician, researcher, and CEO of Michigan Medicine, Dr. Runge looks at what AI, Big Tech, retail medicine, and federal policy are actually doing to American medical care, and what they aren't.
Key Topics:
- AI-driven diagnostics and personalized medicine
- Retail medicine and direct-to-consumer healthcare models
- Gene therapy and next-generation obesity medications
- Digital health transformation and electronic health records
- Policy frameworks for innovation and equity
- The future of academic medicine and clinical research
Coded to Kill
Published: Post Hill Press, 2023
After a decade of development, Drexel Hospital's new Electronic Health Records system is about to become the national standard, housing the real-time medical records of every American. A former NSA operative sees the system as a tool for unimaginable power. Only a loose-knit group of hospital employees with conflicting loyalties can stop him.
Perfect for: Fans of Robin Cook and Michael Crichton, and anyone uneasy about who has access to their medical records.
A bold and visionary roadmap for transforming American healthcare. With clarity and conviction, he explores how emerging technologies can revolutionize care — making it more affordable, equitable, and effective for all.
What's Coming Next
In development: a third nonfiction book, a Substack on epigenetics and biological aging, an open-enrollment Michigan course, and a multi-PI longevity research initiative.
The Negotiation of a Lifetime
Agented by Thomas LeBien · Forbes Books · Heather Wagner, editorial
A general-audience book on epigenetic clocks, the science of biological age, and how to use that measurement to negotiate with your own genes. The premise: aging may not be one-way.
"The question isn't just how long we want to live but how well. In the quest for immortality, perhaps the greatest wisdom is recognizing that a meaningful, healthy life may be the best legacy of all."
The Longevity Switch on Substack
Weekly notes on turning on your best genes
A regular dispatch separating biology from influencer hype. What daily choices actually do, through epigenetic regulation, to shift biological age.
The Longevity Switch MOOC
University of Michigan Center for Academic Innovation
An approved massive open online course (MOOC) through UM's Center for Academic Innovation on epigenetics, maternal mtDNA inheritance, and aging. Three cohorts per year planned.
Living Longer, Living Better
Cardiorespiratory fitness, methylation arrays, and maternal mtDNA inheritance, all in one cohort
A multi-PI initiative with Steven Kunkel, Brian Athey, and Sachin Kheterpal at Michigan, building a "Longevity & Cardiovascular Health Index" from DoDSR/USAFSAM/Cooper/VETS biospecimen archives.
Be first to know when The Longevity Switch launches.
Weekly notes on epigenetic clocks, mitochondrial health, and the science of biological aging — separating biology from influencer hype. Substack and MOOC pre-launch interest both go to the same inbox.
No spam. Email is used only to notify you when the Substack and MOOC go live.
Go Deeper
About Dr. Runge
Forty years across cardiology, medical leadership, and longevity science.
Read more →Active Research
Telomere maintenance, mitochondrial dysfunction, and a multi-PI longevity index at Michigan.
View the research →Speaking
Recent and upcoming keynotes, lifelong-learning institutes, and university lectures.
See engagements →“A bold and visionary roadmap for transforming American healthcare.”— Victor J. Dzau, MD
Praise
Sanjay Gupta, Victor Dzau, Eric Topol, and other healthcare leaders on The Great Healthcare Disruption.
Read all praise →Topic: Longevity
Mitochondria, methylation, and the parts of healthspan you can actually move.
Read the topic →Topic: AI in Medicine
What's actually deployed, where the hype runs ahead of evidence.
Read the topic →Topic: GLP-1s
Semaglutide, tirzepatide, and the cardiometabolic shift they're driving.
Read the topic →Press Archive
Full coverage from C-SPAN, Forbes, Parade, Detroit Free Press, Radio Health Journal, and 50+ outlets.
View press →Media Appearances
Featured across more than 50 outlets: national television, syndicated radio, and the country's leading healthcare publications.
The Great Healthcare Disruption
Available in hardcover, Kindle, and audiobook.
Reaching readers online
Healthcare framing for the lay reader, posted across Instagram, TikTok, and Facebook.